May-ann graduated with a double degree in Business Administration and Accountancy from the University of the Philippines in 1997. She obtained her license as a Certified Public Accountant immediately after. In 2002, she finished her legal education at the UP College of Law and became a member of the Philippine Bar the following year.
May-ann started her law practice in the litigation department of Angara Abello Concepcion Regala & Cruz Law Offices. In 2006, she moved to Bangko Sentral ng Pilipinas to be a legal officer in its Office of the General Counsel and Legal Services. She joined Lim & Leynes, and eventually became a name partner and head of its litigation department in 2011.
Since obtaining her accreditation from the Insurance Commission in 2014, May-ann has been serving as conservator, receiver or liquidator for several insurance and pre-need companies. She is currently a faculty member of the University of the Philippines College of Law and a supervising lawyer at its clinical legal education program, the UP Office of Legal Aid.